Cooling Solutions for the Cleanrooms & Pharmacies Sector
Reliable refrigeration and climate-control systems tailored for cleanrooms and pharmaceutical manufacturing environments.
Green Cooling specialises in providing advanced cooling solutions for the cleanrooms and pharmacies sector. Our systems ensure optimal control of temperature, humidity, pressure and particle contamination while enhancing energy efficiency and operational reliability. With bespoke designs and eco-friendly technology, our solutions help regulated manufacturing and pharmaceutical environments maintain compliance, product integrity and cost-effectiveness.
What Are Cooling Solutions for the Cleanrooms & Pharmacies Sector?
In pharmaceutical and controlled manufacturing environments, the demands on climate-control systems are significantly higher than in standard industrial settings. Cleanrooms require stringent regulation of temperature, humidity, air pressure differentials and airflow patterns in order to prevent contamination, ensure product quality and meet regulatory standards such as ISO 14644 and EU GMP Annex 1.
Cooling solutions in this sector therefore extend beyond basic refrigeration and HVAC—they integrate air filtration, laminar/unidirectional airflow, HEPA filtration, validation and monitoring systems.
Manufacturers of pharmaceuticals, biotech products or medical devices must ensure their controlled-environment systems not only maintain tight tolerances but also offer energy-efficient performance, given the high cost of operating specialist HVAC and refrigeration in such settings.


Benefits of Cooling Solutions for the Cleanrooms & Pharmacies Sector
Regulatory compliance and validation readiness: Systems designed for cleanrooms meet critical standards (ISO 14644, EU GMP Annex 1) and support qualification, monitoring and audit processes.
Enhanced product integrity and reduced contamination risk: Precise climate control and filtration reduce the risk of microbial or particulate contamination, safeguarding product quality.
Optimised operational efficiency: With high energy consumption normally associated with cleanroom HVAC, energy-saving technology, intelligent airflow modulation and low-GWP refrigerants help reduce costs.
Future-proof and flexible facilities: Systems engineered to adapt to changing classifications, manufacturing demands or expansions ensure a longer lifecycle and reduced disruption.
Our Cooling Solutions for the Cleanrooms & Pharmacies Sector
Green Cooling offers a range of bespoke solutions, including:
Precision HVAC & Refrigeration Systems
We design and supply high-performance HVAC and refrigeration units tailored for controlled environments. Whether it’s chilled-water systems, precision chillers or dedicated AHUs with HEPA/ULPA filtration, our solutions deliver the tight temperature and humidity control required.
Humidity & Pressure Control Modules
Maintaining correct humidity and pressure differentials is essential—especially for sterile or high-risk areas. Our designs include variable-air-volume (VAV) modules, differential pressure monitoring, and aseptic airflow strategies to meet cleanroom classifications.
Cleanroom-Grade Airflow Systems
From laminar flow ceilings to clean-zone containment, our systems ensure that airflow patterns, air-change rates and filtration meet or exceed the required cleanliness classification.
Energy-Saving Technology
We integrate the latest in low-GWP refrigerants, variable-speed drives, demand-controlled filtration and real-time monitoring to reduce operating costs without sacrificing performance.
Installation & Maintenance
Our service offering covers not just design and installation, but also commissioning, validation support (IQ/OQ/PQ), ongoing maintenance and monitoring programmes to keep your cleanroom system compliant, efficient and reliable throughout its lifecycle.
Industries We Serve
Our Cleanrooms & Pharmacies cooling solutions are ideal for:
Pharmaceutical Manufacturing
Precision cooling solutions that support strict environmental control for compliant drug production.
Biotech & Life Science Facilities
Reliable climate-control systems designed to maintain stable conditions for sensitive research and processes.
Medical Device Cleanrooms
Specialist cooling to protect sterile manufacturing zones and ensure consistent product quality.
ISO-classified Manufacturing Zones
Fully compliant cooling systems engineered to meet ISO cleanroom standards across controlled environments.
Why Choose Green Cooling?
With decades of experience in high-precision climate-control and low-carbon refrigeration, Green Cooling brings expert engineering, regulatory-aware design and full-lifecycle support to every cleanroom and pharmacy project. We offer:
- Demonstrated expertise in highly regulated sectors with controlled environments
- Bespoke, fully-integrated systems tailored for performance, sustainability and compliance
- Comprehensive service—from concept and design through to installation, commissioning, monitoring and maintenance
- A partner committed to reducing your environmental footprint while enhancing your manufacturing efficiency

FAQs About Cooling Solutions for the Cleanrooms & Pharmacies Sector
The required classification depends on your manufacturing process and risk assessment. Cleanrooms are classified under ISO 14644-1 (from Class 1 to Class 9) and pharmaceutical zones use Grades A-D (as per EU GMP Annex 1).
By employing systems such as demand-controlled air change rates, free or partial free-cooling, variable-speed drives and careful validation of airflow/pressure regimes. These allow you to maintain compliance while optimising power use.
Robust systems must support traceability, audit trails, and have instrumentation for real-time monitoring of temperature, humidity, pressure and particulate counts. They should facilitate qualification stages (DQ, IQ, OQ, PQ) to meet regulatory expectations.
Enhance Your Cleanroom or Pharmaceutical Environment with Green Cooling
Whether you’re planning a new facility, upgrading an existing clean zone or looking to improve energy efficiency and regulatory compliance, Green Cooling can help you design and deliver a climate-control solution that meets your operational and sustainability goals.
Ready to Start Your Cooling Journey?
Contact our cleanroom climate specialists today for a free consultation and let us help you build the robust, compliant and efficient controlled-environment system your operation requires.